UST-Legazpi is a Catholic higher educational institution devoted to the holistic formation of its students through academic excellence, moral formation, and emotional maturity.

UST-Legazpi offers pre-elementary, elementary, high school (General Curriculum, Special Program in the Arts, and PAASCU Level III-candidate Science High School), Senior High School, and twenty–three (23) programs (in the College of Arts, Sciences and Education; College of Business Management and Accountancy; College of Health Sciences; and College of Engineering, Architecture and Fine Arts), the newest of which are the BS Pharmacy, the first and only program in the Region, and BS Medical Technology, both supervised by UST-Manila. The Peñaranda campus hosts the College of Business Management and Accountancy, College of Law (the Center of Excellence in Legal Education in Bicol), the Graduate School, and the Center for Continuing Education.